Seoul National University, Seoul, Republic of Korea
Department of Biomedical Sciences
Thesis: Exploration of the Role of Regulatory T cells in Various Pathogenic Contexts
Advisor: Chung-Gyu Park, M.D., Ph.D.
| Funding Agency / Sponsor | Project | Period | Budget (USD) | Role / Contribution |
|---|---|---|---|---|
| Korea Drug Development Fund (KDDF) | Anti-CD40 antibody lead selection and optimization (multiple sclerosis) | 2021–2023 | ~$571,000 | Lead proposal writer (>90% of proposal & execution) |
| Korea Drug Development Fund (KDDF) | Anti-CD40 lead compound (PB101): efficacy and pharmacodynamic biomarkers (pemphigus vulgaris) | 2022–2024 | ~$321,000 | Lead proposal writer (>90% of proposal & execution) |
| Ministry of SMEs and Startups (MSS) | Scale-up Funding for Tech Commercialization | 2022–2023 | ~$222,000 | Lead proposal writer; managed >90% of execution |
| Ministry of SMEs and Startups (MSS) | Early-stage startup R&D: anti-CD40 biologic (PB-40N) to prevent anti-drug antibodies | 2021–2022 | ~$74,000 | Lead proposal writer & core researcher |
| NAVER Corporation | Engineered regulatory T cells for immune-mediated diseases (PB20X_Treg) | 2023–2026 | ~$128,000 | Proposal & study design (~50%) |
| Funding Agency / Sponsor | Project | Period | Budget (USD) | Role / Contribution |
|---|---|---|---|---|
| Ministry of Science and ICT (MSIT) | Multi-layered immune-disease single-cell map for molecular target discovery (SCAID, A9-22-1-05) | 2022–2028 (3+3) | ~$1.6M | Participated in proposal writing (>30%) |
| Ministry of Education (MOE) & Ministry of Science and ICT (MSIT) | Laboratory-Specialized Tech-Transfer & R&BD Grant | 2020–2021 | ~$40,000 | Grant writing, experimental design & technical validation |
| Year | Mentee / role at time | Current affiliation | Research training |
|---|---|---|---|
| 2013 | Sung Ha Lim, M.D., Ph.D. Student intern |
Postdoctoral Fellow; Laboratory of Shadmehr Demehri, M.D., Ph.D.; Department of Dermatology, Massachusetts General Hospital; Harvard Medical School, Boston, MA, USA | Cell culture, Western blotting, flow cytometry, and C57BL/6 mouse breeding. |
| 2014 | Soyoung Jeong, Ph.D. Student intern |
Postdoctoral Associate; Medical Research Center, Seoul National University, Seoul, Republic of Korea | Cell culture, flow cytometry, and in vivo mouse experiments. |
| 2016 | Sowon Choi, M.S. Incoming graduate student |
Ph.D. Candidate; Department of Biomedical Sciences; Seoul National University Graduate School, Seoul, Republic of Korea | Mouse pancreatic islet isolation, pancreatic islet beta-cell functional assays, and ion channel assays. |
| 2021 | Hyo Jeong Nam, M.S. Incoming graduate student |
Visiting Scholar; Laboratory of Seunghee Kim-Schulze, Ph.D.; Department of Immunology and Immunotherapy; Icahn School of Medicine at Mount Sinai, New York, NY, USA; Ph.D. Candidate; Department of Biomedical Sciences; Seoul National University Graduate School, Seoul, Republic of Korea | GeoMx DSP, T-cell functional assays, and single-cell RNA sequencing (scRNA-seq) data analysis using R. |
| 2021 | Beom Keun Cho, M.S. Incoming graduate student |
Ph.D. Candidate; Department of Biomedical Sciences; Seoul National University Graduate School, Seoul, Republic of Korea | GeoMx DSP, mouse breeding, cell culture, T-cell functional assays, and scRNA-seq data analysis using R. |
| 2021 | Minji Kang, Ph.D. Incoming graduate student |
Postdoctoral Associate; Transplantation Research Institute; Seoul National University Medical Research Center, Seoul, Republic of Korea | GeoMx DSP spatial transcriptomics data analysis and T-cell functional assays. |
| 2021 | Jung Ho Lee, M.S. Incoming graduate student |
Visiting Scholar; Laboratory of Ulrich von Andrian, M.D., Ph.D.; Department of Immunology, Harvard Medical School, Boston, MA, USA; Ph.D. Candidate; Department of Biomedical Sciences; Seoul National University Graduate School, Seoul, Republic of Korea | scRNA-seq data analysis using R. |
| 2021 | Hyun Seung Choi, M.S. Incoming graduate student |
Ph.D. Candidate; Department of Biomedical Sciences; Seoul National University Graduate School, Seoul, Republic of Korea | scRNA-seq data analysis using R. |
| 2022 | Yuji Lee, M.S. Incoming graduate student |
Ph.D. Candidate; Department of Biomedical Sciences; Seoul National University Graduate School, Seoul, Republic of Korea | Regulatory T-cell suppression assays and scRNA-seq data analysis using R and machine-learning models. |
| 2022 | Sanha Hwang, M.S. Incoming graduate student |
Ph.D. Candidate; Department of Biomedical Sciences; Seoul National University Graduate School, Seoul, Republic of Korea | Regulatory T-cell suppression assays and scRNA-seq data analysis using R and machine-learning models. |
| 2022 | Dongjun Kim, M.S. Incoming graduate student |
Ph.D. Candidate; Department of Biomedical Sciences; Seoul National University Graduate School, Seoul, Republic of Korea | Regulatory T-cell suppression assays and scRNA-seq data analysis using R and machine-learning models. |
| 2022 | Yewon Moon, M.S. Incoming graduate student |
Ph.D. Candidate; Department of Biomedical Sciences; Seoul National University Graduate School, Seoul, Republic of Korea | Regulatory T-cell suppression assays and scRNA-seq data analysis using R and machine-learning models. |
| 2022 | Karoliina Eliisa Ruhno, M.S. Incoming graduate student |
Senior Researcher; IMBiologics, Seoul, Republic of Korea | Regulatory T-cell suppression assays. |
| 2023 | Moonki Chae, M.S. Student intern |
Ph.D. Student; Department of Pathology; Johns Hopkins University, Baltimore, MD, USA | Immune-cell culture, flow cytometry, and scRNA-seq data analysis using machine-learning models and AI tools. |
| 2023 | Sung Bin Bae, M.S. Incoming graduate student |
Researcher; Yuhan Corporation, Seoul, Republic of Korea | Cell culture, flow cytometry, and GeoMx DSP spatial transcriptomics data analysis. |
| 2024 | Mi Jeong Oh, M.S. Manager, PB Immune Therapeutics |
Manager; PB Immune Therapeutics, Seoul, Republic of Korea | Experimental design for animal sample collection, ELISA and SPR assay design, and 10x Genomics scRNA-seq. |
| 2024 | Eun Sol Jo, B.S. Assistant Manager, PB Immune Therapeutics |
Assistant Manager; PB Immune Therapeutics, Seoul, Republic of Korea | Animal experiment design and evaluation of a mouse model of experimental autoimmune encephalomyelitis (EAE). |